The best happy hour in San Diego is at Mister A's, and it has everything to do with the view. Feast your eyes on the calm, glittering bay and watch the planes land and take off from the famously short San Diego airport runway. The restaurant is located on the 12th floor, and I would categorize it as VERY WHITE TABLECLOTH. Translation: stuffy crowd. That is why I recommend their happy hour (Sunday - Thursday, 2:30 - 6:00pm). The patio wraps around the entire building, so you shouldn't have a problem finding a spot.